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Hydrocodone is an opioid narcotic , and acetaminophen is an analgesic pain reliever. Both drugs are used to reduce pain. Acetaminophen-hydrocodone oral tablet may make you feel sleepy, dizzy, or lightheaded. Avoid driving a car or using machinery until you know how your body reacts to this medication. Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following:.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects.

This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Acetaminophen-hydrocodone oral tablet can interact with other medications, vitamins , or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Taking certain drugs with acetaminophen-hydrocodone increases your risk of drowsiness, dizziness, tiredness, and reduced physical and mental function.

If you need to use one of these drugs with acetaminophen-hydrocodone, the dosage of one or both drugs should be reduced. Taking this medication with drugs that increase the amount of a chemical called serotonin in your body can cause a serious problem. This problem, called serotonin syndrome, can be fatal. Tell your doctor if you are taking any of these medications:. Taking this medication with drugs that can inhibit activity of certain liver enzymes can increase the amount of hydrocodone in your body and cause more side effects.

You may have increased breathing problems or drowsiness. Examples of these drugs include:. Taking this medication with drugs that can increase activity of certain liver enzymes can lower the amount of hydrocodone or acetaminophen in your body.

You may need a higher dose of this medication to control your pain. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Taking it again could be fatal cause death. Drinking alcohol while taking this medication may cause:.

For people with head injury: If you have a head injury, hydrocodone may cause increased pressure in your brain and cause breathing problems.

For people with stomach problems: Use caution taking this drug if you have intestinal obstruction, ulcerative colitis, or constipation.

This medication may worsen your symptoms. For people with severe kidney disease: This drug may build up in your body, which can cause trouble breathing and other side effects. For people with lung disease: If you have lung disease, you might have trouble breathing if you take this medication. For people with severe liver disease: If you have severe liver disease, your risk of liver failure is increased. Also, this drug may build up in your body, which can cause trouble breathing and other side effects.

For people with prostate enlargement: If you have an enlarged prostate, taking acetaminophen-hydrocodone may cause increased difficulty in urination. Error Email field is required. Error Include a valid email address. To provide you with the most relevant and helpful information and to understand which information is beneficial, we may combine your e-mail and website usage information with other information we have about you. If we combine this information with your PHI, we will treat all of that information as PHI, and will only use or disclose that information as set forth in our notice of privacy practices.

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Please try again. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Updated visitor guidelines. You are here Home » acetaminophen and hydrocodone. Top of the page. Norco slide 5 of 29, Norco,. Norco slide 26 of 29, Norco,. Norco slide 27 of 29, Norco,.

Norco slide 28 of 29, Norco,. Xodol slide 29 of 29, Xodol,. What is the most important information I should know about acetaminophen and hydrocodone? What is acetaminophen and hydrocodone? Acetaminophen and hydrocodone is a combination medicine used to relieve moderate to severe pain. Acetaminophen and hydrocodone may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking acetaminophen and hydrocodone? How should I take acetaminophen and hydrocodone? What happens if I miss a dose?

What happens if I overdose? What should I avoid while taking acetaminophen and hydrocodone? Do not drink alcohol. Dangerous side effects or death could occur. What are the possible side effects of acetaminophen and hydrocodone? What other drugs will affect acetaminophen and hydrocodone? Where can I get more information? Your doctor or pharmacist can provide more information about acetaminophen and hydrocodone.

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