Which is better nexium or pantoprazole

Esomeprazole 40 mg provides more effective intragastric acid control than lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg and rabeprazole 20 mg in patients with gastro-oesophageal reflux symptoms. Eur J Clin Pharmacol. Esomeprazole 20 mg provides more effective intragastric Acid control than maintenance-dose rabeprazole, lansoprazole or pantoprazole in healthy volunteers.

Clin Drug Investig. Effect of esomeprazole 40 mg vs. Reanalysis of intragastric pH results based on updated correction factors for Slimline and Zinetics 24 single-use pH catheters. User Username Password Remember me. Font Size. Notifications View Subscribe.

Article Tools Print this article. Indexing metadata. How to cite item. Finding References. Email this article Login required. Comparative study of pantoprazole and esomeprazole for erosive gastroesophageal reflux disease: a prospective study. Abstract Background: The objective of this study was to compare the efficacy of pantoprazole and esomeprazole to heal and relief from erosive esophagitis EE disease related symptoms.

Full Text: PDF. Sachs G. Proton pump inhibitors and acid-related diseases. The most common side effects of Protonix are headache, diarrhea, nausea, abdominal pain, vomiting, gas, dizziness, and joint pain. Common side effects of Nexium include headache, diarrhea, nausea, gas, abdominal pain, constipation, and dry mouth. Serious side effects of PPIs are often associated with long-term use. Serious side effects may include osteoporosis-related bone fractures, vitamin B12 deficiency, and low magnesium levels hypomagnesemia.

Frequency is not based on data from a head-to-head trial. This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more. Protonix and Nexium, like other PPIs, interact with many of the same medications. These PPIs should be monitored or avoided with other drugs that are dependent on stomach acidity for absorption.

Drugs that are dependent on stomach acidity for absorption include iron salts, erlotinib, ketoconazole, and mycophenolate mofetil. Protonix and Nexium can also interact with antiretroviral drugs, or drugs that are often used to treat HIV. PPIs can increase or decrease blood levels of antiretroviral drugs, which can lead to an increased risk of toxicity or decreased effectiveness with antiretroviral drugs.

Nexium should be monitored or avoided with diazepam since it can increase blood levels of diazepam and lead to an increased risk of adverse effects. The use of Nexium and clopidogrel together should also be avoided.

Nexium can decrease how well clopidogrel works in the body, which can increase the risk of blood clots. The long-term use of PPIs may lead to an increased risk of bone fractures, especially in people who have already been diagnosed with osteoporosis.

Bone mineral density may need to be monitored during long-term treatment with PPIs. Some patients have experienced acute tubulointerstitial nephritis TIN while taking Protonix or Nexium. Nephritis is the inflammation of the kidneys, which can lead to decreased kidney function. The use of PPIs may be linked to an increased risk of Clostridium difficile-associated diarrhea.

Those who experience persistent diarrhea may need to be monitored, especially in a hospital setting. Taking Protonix or Nexium can increase the risk of low blood levels of magnesium hypomagnesemia or vitamin B12 vitamin B12 deficiency. There is an increased risk of hypomagnesemia and vitamin B12 deficiency in those on long-term treatment with PPIs. Consult your healthcare provider for other possible warnings and precautions before taking a PPI.

Protonix is available as a delayed-release tablet and liquid suspension. The generic name of Protonix is pantoprazole. It is available with a prescription or over the counter. Nexium primarily comes as a delayed-release capsule or a liquid suspension. The generic name of Nexium is esomeprazole.

However, they contain different active ingredients and come in different formulations. However, generic omeprazole may be less expensive than Prilosec OTC. Work with your doctor or pharmacist to decide which PPI is best for you.

In addition to cost, consider things like:. A link to possible dementia risk was reported in , but a larger confirmatory study in determined that there was no increased risk of dementia from using PPIs.

Many people experience excess acid production when they stop using PPIs. At the end of the recommended treatment duration, you should taper off of the medication gradually.

Work with your doctor to do so. Before taking either medication, talk to your doctor to learn about the risk factors and drug interactions associated with them. Always tell your doctor about all the drugs, herbs, and vitamins you take. Prilosec and Nexium can interact with other medications you might be taking.

The U. Food and Drug Administration FDA has issued a warning that the drug in Prilosec reduces the effectiveness of the blood thinner clopidogrel Plavix. Other drugs can interact with Nexium or Prilosec, but may still be taken with either drug.

Tell your doctor if you take any of these drugs so they can evaluate your risk:. Lifestyle changes should be your first steps in controlling GERD and heartburn. You may want to try:. Over time, long-term GERD can lead to esophageal cancer. GERD gastroesophageal reflux disease is a chronic form of heartburn. Learn about symptoms and treatment.

Acid reflux happens when stomach acid backs up into your esophagus. Learn how to prevent and treat it with lifestyle changes, medications, or surgery…. Prilosec and Zantac both reduce acid levels in the stomach to relieve symptoms of acid reflux. Find out how these drugs are alike and different.

Baking soda can temporarily relieve acid reflux. But it can also cause unintended side effects. Find out how much baking soda you should take for acid….